Ngcobo was substituted off just over 70 minutes into his full PSL debut on Friday evening as Chiefs played to a 1-1 draw with SuperSport United at the Mbombela Stadium.
The Amajita star looked in some discomfort as he was forced off on a stretcher, and was subsequently replaced by Philani Zulu.
The club have since confirmed an Achilles injury for the 19-year-old, who recently helped the national under-20 side qualify for the FIFA U-20 World Cup in Poland.
The former Amakhosi reserve team captain is set to undergo further tests on Monday to determine the exact extent of his setback.
— Kaizer Chiefs (@KaizerChiefs) March 18, 2019
Chiefs remain without Itumeleng Khune, Lebogang Manyama, Happy Mashiane, Jospeh Molangoane, Erick Mathoho and Lorenzo Gordinho due to an assortment of injuries.