Kane, 21, will make his first Three Lions start tonight, having netted 79 seconds into his debut in the 4-0 win over Lithuania on Friday.
The Tottenham striker - who will battle the likes of Giorgio Chiellini and Leonardo Bonucci in Turin - has scored 29 goals in all competitions for the Londoners this season.
"With Italian defenders, especially the clever defenders, they'll do anything to try and stop you," said Rooney, who came up against the Azzurri at the World Cup last year. "I think Italy's a passionate country. They love their football, they are probably the closest in Europe to South American teams.
"They're tough to play against, well-organised, they make it as difficult as they can for us. Italy are the best in Europe at doing that.
"You need to be aware of that and not get frustrated. At the minute what Harry is doing he needs to continue doing.
"He's taking the ball, he's a handful for defenders, he's running at the defenders and getting shots off at goal. That's all he has to do tomorrow. I'm sure if he does that the way he has been, he'll be fine."