The Buccaneers will be confident of reaching the group stages, having won the first leg of the play-off tie in Mali 2-0 a fortnight ago.
The man in charge for the match is Neant Alioum, a 32-year-old who has been blowing the whistle since 2008 and who officiated in the 2014 FIFA World Cup qualifiers.
Evarist Menkouande and Yanoussa Moussa will be running the lines.
The match between Pirates and AS Khaloum will be live on SuperSport4 from 3pm.