Bayern Munich resumed Bundesliga duties with a surprise 2-1 loss to FC Augsburg at the WWK Arena on Friday evening.
With Joshua Kimmich quarantining, Bayern opted to start the likes of Niklas Sule, Kingsley Coman and Alphonso Davies on the bench.
The Bavarians were stunned midway through the first half after Mads Pedersen helped a flick on past goalkeeper Manuel Neuer following a smart run in.
Solid goalkeeping from Rafal Gikiwicz prevented Bayern an instant response from Omar Richards' low rasping attempt off a well-weighted layoff by Thomas Muller.
Augsburg shocked the all-conquering Bundesliga outfit again when Andre Hahn leaped strongly over Lucas Hernandez on 35 minutes to head Iago Borduchi's ball home.
Julian Naglesmann's men managed to cut the home side's tally after three minutes through a low close-range volley by Robert Lewandowski from a supply by Muller.
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A slow start to the second half came to life five minutes in when Lewandowski snapped a loose ball from five-yards out over the top from a deep-rooted ball into the area by Benjamin Pavard.
The Bavarians named a double substitution minutes apart, with Richards withdrawn for Davies and Jamal Musiala introduced in the place of Marcel Sabitzer.
Amidst a passive start to the second spell, Bayern's frustrations continued with Davies missing three clear openings from point-blank range within the latter minutes.
Augsburg escaped another threat from the title holders before fulltime after a punch by Gikiewicz from Musiala's shot met Leon Goretzka, who went wide of target.
The Bavarians continued to probe a turnaround with time running out, but the host held on tight to claim a shock victory.