Bayern Munich missed the chance to claim the Bundesliga title on Saturday following a 2-1 loss at the hands of Mainz 05 at the Coface Arena.
Mainz broke the deadlock minutes from the start of the match through Jonathan Burkardt before Robin Quaison doubled their advantage a little before the halftime period.
Bayern were given a consolation through the returning Robert Lewandowski, as their next fixture come against Borussia Monchengladbach next Saturday, while Mainz tackle Hertha Berlin.
Bayer Leverkusen continued their winning streak with a 3-1 victory over Eintracht Frankfurt at the BayArena to maintain a top-four push.
A goalless first half was washed away as efforts from Leon Bailey, Lucas Alario and Kerem Demirbay put the host on the front, whilst Andre Silva netted the visiting side's consolation goal.
A ten-man Borussia Dortmund maintained their top-four chances at the Volkswagen Arena through a 2-0 win over Vfl Wolfsburg.
Dangerman Erling Braut Haaland gave the Black and Yellow brigade the lead early on and went on to complete his brace in the latter stages of the second half.
More drama followed the visitors after Jude Bellingham was given his marching orders for a second bookable offence midway in the second half, as it finished 2-0 in the end.
SC Freiburg were unable to collect back-to-back wins in the league after settling for a 1-1 draw against TSG Hoffenheim.
The away side entered the halftime interval ahead through the expertise of Andre Kramaric, but a spot kick from Vincenzo Grifo handed Freiburg a stalemate.
It's a result that leaves either of the sides in the bottom-half of the table, with Freiburg in ninth and Hoffenheim in eleventh spot.
Union Berlin brought their top-six hopes in the league to life again following a 3-1 victory over struggling Werder Bremen.
A goalless first half was effectively forgotten following a stupendous second half hat-trick from Joel Pohjanpalo.
The visiting side's sole consolation came thanks to Theodor Gebre Selassie, but the day belonged to Berlin in the end.