Messi's wait for a major international trophy with Argentina is finally over, with the 34-year-old also winning the Player of the Tournament prize before the final was played on Sunday.
Read: UEFA's official best XI of Euro 2020
The Albiceleste captain scored four goals at the tournament in Brazil to win the Golden Boot, while his return of five assists was also unmatched, according to GiveMeSport.
With the South American Football Confederation (CONMEBOL) having now announced the best XI of the 2021 Copa, it is thus no surprise to see Messi in the selection. But who joins him?
Scroll through the gallery above to see CONMEBOL's official 2021 Copa America best XI
Brazil's Neymar and his teammates were defeated in the final against Argentina as the 29-year-old's wait for a major international trophy continues. The Selecao winger's dazzling displays did not go unnoticed, though, as he leads the team of the tournament's front line with six-time Ballon d'Or winner Messi.
Former Arsenal goalkeeper David Ospina, Claudio Bravo and Ederson caught the attention with good performances between the poles, but it was Aston Villa's Emiliano Martinez who shone above all the rest to be named the best XI's shot-stopper.
After all, he played a key role in his nation's triumph, and collected the Golden Glove award with only two goals conceded in six matches.
Other big names in the team of the tournament include Real Madrid's Casemiro and Paris Saint-Germain's Marquinhos, who provided the defensive solidity to help the Selecao progress to the final, where they fell short to Argentina – scroll through the gallery above to see the official best XI of the 2021 Copa America, as confirmed by CONMEBOL!