Spain opened up their 2022 FIFA World Cup Qualifying campaign in Group B with a 1-1 draw against Greece at the Los Carmenes on Thursday evening.
La Roja took the lead into the halftime period as Alvaro Morata found the breakthrough, but the Greeks came back and levelled from the spot through Anastasios Bakasetas.
Luis Enrique's men will now turn focus to a tricky trip away to Georgia on Sunday in the second match of their qualifying journey.
Italy started their road to the 2022 World Cup finals on a positive note after two first-half goals ensured a 2-0 win over the Northern Ireland in Group C.
The goals came inside the first 20 minutes through Domenico Berardi and Ciro Immobile, as the Italians sit second in the group standings.
Their next assignment is on Sunday away to Bulgaria in their second match of the group stage journey.
England smashed San Marino 5-0 in their first World Cup qualifying clash in Group I at the Wembley Stadium.
The Three Lions were three goals up at the break through James Ward-Prowse and Dominic Calvert-Lewin and Raheem Sterling.
Calvert-Lewin went on to complete his brace early in the second half whilst substitute Ollie Watkins finished off the rout to lead his nation to the top of the group.
Germany also made a winning start towards the finals in Qatar next year after cruising past Iceland 3-0 in a Group J clash in Duisburg.
Goals in the first ten minutes from Leon Goretzka and Kai Havertz put the Germans on the way before Ilkay Gundogan complemented the evening's work near the end.
Poland and Hungary cancelled out each other with an entertaining 3-3 draw in their first World Cup qualifying match in Group I.
Hungary drew first blood through Roland Sallai and Adam Szalai, but it was wiped out by Krzysztof Piatek and Kamil Piatkowski.
Willi Orban restored the hosts' lead late in the second half, but Robert Lewandowski fired in the equaliser as Attila Fiola picked up a red card at the end of the match.