Germany brushed aside Iceland 4-0 to make it five wins from six in Group J.
The four-time world champions raced into a two-goal lead in the first half through Serge Gnabry and Antonio Rudiger.
Leroy Sane and Timo Werner got on the scoresheet for Die Mannschaft in the second half to wrap up a good 2022 FIFA World Cup qualifying win.
Belgium did not have it all their own way as they sneaked past Belarus 1-0 on Wednesday evening.
Dennis Praet netted the only goal of the encounter in the 33rd minute to keep the Red Devils top of their group.
Poland scored a dramatic late equaliser to break England's winning run in Group I.
It took a while but the Three Lions eventually broke the deadlock through captain Harry Kane in the 72nd minute following an assist from Kyle Walker.
However, in the second minute of stoppage time, Damian Szymanski headed home Robert Lewandowski's cross to snatch a point for the Poles.
Italy came away comfortable 5-0 victors over Lithuania to cement top spot in Group C.
Moise Kean got on the scoresheet twice, while an own goal from Edgaras Utkus and further strikes from Giacomo Raspadori and Giovanni Di Lorenzo completed the rout for the European champions.
Spain got back to winning ways in Group B after seeing off Kosovo 2-0.
Pablo Fornals scored in the 32nd minute before Ferran Torres made sure of the points in the 88th minute to continue his hot run of form.