Algeria remain unbeaten at the top of Group A after trouncing Niger 6-1 courtesy of two goals apiece by Riyad Mahrez and Islam Slimani at Stade Mustapha Tchaker.
Sofiane Feghouli and an own goal by Zakariya Souleymane were the other goals for the Desert Foxes in between a double by Mahrez and Slimani while Daniel Sosah scored what proved to be a consolation goal for Niger.
Carlos Queiroz enjoyed a winning start in the qualifiers with Egypt, who edged Libya 1-0 to climb to the top of Group F at Borg El Arab Stadium.
After a goalless first stanza, Omar Marmoush eventually broke the deadlock for the Pharaohs early in the second stanza and that was enough to hand Queiroz's charges the three points, as they toppled Libya by one point at the top of the section.
Cameroon got their Group D campaign back on track with a 3-1 win over Mozambique at Stade Ominisports.
Eric Maxim Choupo-Moting broke the deadlock for the Indomitable Lions just before the half-hour mark and doubled their lead early in the second stanza before Karl Toko Ekambi secured the three points just after the hour-mark.
Geny Catamo got a consolation goal for the Mambas in the last nine minutes and the visitors finished the game with ten men after Danilo Muze was red-carded two minutes before time.
Unbeaten Côte d'Ivoire maintained top spot in Group D after a comprehensive 3-0 victory over Malawi at Orlando Stadium.
Max Gradel broke the deadlock for the Elephants nine minutes before the half-time break.
Ibrahim Sangare settled the nerves with the second goal before Jeremie Boga got the third goal in stoppage time.
Angola got their first victory in Group F after thrashing Gabon 3-1 at Estadio 11 de Novembro.
Zini broke the deadlock for Angola in the 25th minute and Papel Ary doubled their lead early in the second stanza.
Axel Meye pulled a goal back for Gabon in the last seven minutes but only for Jonathan Buatu to seal victory for the Southern African side in stoppage time with their third goal.
Burkina Faso thrashed Djibouti 4-0 at Stade de Marrakech on Friday.
Abdoul Tapsoba broke the deadlock for the Stallions on the stroke of half-time and doubled their lead early in the second stanza.
Issa Kabore and Mohamed Konate followed through with two quick goals for Burkina Faso before the hour-mark to put the game out of sight.