Sevilla advanced to the UEFA Europa League final after rallying from behind for a 2-1 win over Manchester United on Sunday evening.
United made just two changes from the win over FC Copenhagen in David De Gea and Victor Lindelof, while the Spaniards were unchanged from their win over Wolverhampton Wanderers.
Bruno Fernandes gave the Red Devils a dream start on nine minutes after blasting in from the penalty spot after Marcus Rashford went down in the area.
Sevilla rallied back four minutes to the half-hour mark when former AC Milan and Liverpool midfielder Suso charged in at the near post to cushion home Sergio Reguilon's delivery.
Rashford threatened to restore his side's lead inside the last five minutes of the half with a swerving effort, but Sevilla shot-stopper Yassine Bounou dived down to turn to safety.
Sevilla were still on the back-foot following the restart, as Fernandes set-up Mason Greenwood for a crack but Bounou quickly charged off his goal-line to avert the scare.
Anthony Martial was sent clear by Pogba following a one-two on 52 minutes, but Bounou denied the French forward from point-blank range with goal-line rush.
Julen Lopetegui looked to swing the spell of play four minutes later with an attacking substitution in Luuk de Jong and Munir El Haddad with Lucas Ocampos and Youssef En-Nesyri sacrificed.
It worked as the Spaniards seized ahead in the last 12 minutes when de Jong side-footed home Jesus Navas' cross from close-range as United went to sleep at the back.
The Red Devils nearly allowed a third in the remaining minutes, but Franco Vazquez volleyed over following Ever Banega's cross as Sevilla stunned their English counterparts once again.