Liverpool extended their lead at the top of the Premier League table to nine points after beating rivals Manchester City 2-0 on Sunday evening.
The Reds recalled Luis Diaz to join Mohamed Salah and Cody Gakpo in attack while injuries at the back saw Trent Alexander-Arnold and Joe Gomez also brought back.
City, meanwhile, preferred Stefan Ortega in goal instead of Ederson while Matheus Nunes was recalled to play alongside Rico Lewis, Phil Foden, Bernardo Silva and Erling Haaland going forward.
Liverpool showed more determination in the early stages as Virgil Van Dijk had a header that came off the crossbar.
The hosts were spurred on as a minute later Gakpo gave them the lead with a tap-ina at the back post after a teasing cross by Salah.
Pep Guardiola's charges were subdued, under attack and only came close to getting on the scoresheet just before the half-time break after Lewis had a low drive that missed the far post by a whisker.
Arne Slot's charges went to the interval with a narrow lead but they would have felt they deserved more, as The Citizens needed to lift up their attacking game from the break.
Liverpool were threatening from the off early in the second stanza, as they looked to exploit spaces behind City's defence, who were desperate to get back into the game.
Salah had a big chance to make it 2-0 for The Reds around the hour-mark after he caught Ortega off his line but he fired his shot over the crossbar.
Liverpool continued to absorbed the pressure and with 15 minutes to go, they brought on the fresh legs of Darwin Nunez in place Gakpo.
The introduction of Nunez by The Reds paid off three minutes later after the Uruguayan was brought down in the box by Ortega, who conceded a penalty.
Salah stepped up and made it 2-0 for Slot's men with a low strike from the penalty spot.
Guardiola eventually brought on Kevin De Bruyne and Jack Grealish to rescue the game in the last ten minutes.
De Bruyne should have pulled a goal back for City a moment later after he latched onto a mistake by Van Dijk to go through on goal but he was denied by shot-stopper Caoimhin Kelleher from point-blank range.
The Reds held on in the end as they pulled nine points clear at the top and 11 points ahead of fifth-placed Citizens.