Brugge showed several determined displays Europe's elite club competition to earn third spot in Group A ahead of Turkish Super Lig giants Galatasaray.
And a two-legged round of 32 fixture with the most successful club in English football history now lays await for the Belgian league leaders.
Tau, after impressing in a cameo appearance to set up a winning goal against Beveren this weekend, as predicted, earns a start upfront with Nigeria forward Emmanuel Dennis.
Brugge's key man will, however, be the industrious Hans Vanaken in the playmaker role behind the African duo.
The towering Belgium international midfielder has scored 16 goals across all competitions this season.
Brugge: Mignolet; Dele, Mechele, Kasonou, De Cuyber, Balanta, Rits, Mata, Vanaken, Dennis, Tau.
SUBS: Krmencik, Okereke, Openda, Schrijkvers, Sobol, Mirovic, Ricca, Horvath.
United: Romero; Dalot, Lindelof, Maguire, Shaw, Williams, Mata, Matic, Andreas, Lingard, Martial.
SUBS: De Gea, Bailly, Wan Bissaka, Fred, Fernandes, James, Ighalo.