South Africa's Percy Tau started as Club Brugge played to a 1-1 draw against Manchester United in the UEFA Europa League last 32 first-leg on Thursday evening.
Brugge took the lead in the 15th minute through Hans Vanaken before Anthony Martial got United a vital away goal just before halftime.
Inter Milan took a slender first-leg advantage against Bulgarian side Ludogorets after sealing a 2-0 win.
The Italians struggled to break through for large parts until Christian Eriksen came to the fore late in the second half while a late penalty from Romelu Lukaku sealed the deal ahead of next Thursday's return-leg.
Last season's UEFA Champions League semi-finalists were stunned 2-0 by Spanish outfit Getafe at the Alfonso Perez Stadium.
Getafe went into the halftime break leading through Deyverson's 37th minute strike before Kenedy made the game safe deep late in the second stanza.
Eintracht Frankfurt have one foot in the last 16 after a commanding 4-1 first-leg victory over Red Bull Salzburg.
Daichi Kamada hit a first-half double before completing his hat-trick early in the second half to go along with Filip Kostic's solitary strike.
The Austrians got a consolation in the remaining minutes through Hwang Hee-chan, who netted from the penalty spot.
FC Copenhagen and Scottish giants Celtic settled for a 1-1 first-leg stalemate at the Parken Arena in Copenhagen.
Celtic were ahead at the break through Odsonne Edward's 14th minute finish but Dame N'Doye drew the hosts level inside the 56th minute.
CFR Cluj and Sevilla also played to a 1-1 draw in their first-leg encounter at the Dr. Constantin Radulescu Stadium.
A 59th minute penalty from Ciprian Deac gave the Romanians the lead before Youssef En-Nesyri brought the LaLiga outfit level from the spot eight late on.
Sporting Lisbon went within touching distance of the last 16 following a 3-1 first-leg win over Istanbul Basakesehir F.K.
Goals from Sebastian Coates, Andraz Sporar and Luciano Vietto did the business for the Portuguese giants, while Edin Visca netted for the Turks.
Shakhtar Donetsk grabbed a narrow 2-1 first-leg victory over Benfica at the SportKomplez Metalist in Donetsk.
Shakhtar took the lead through Alan Patrick early in the second half but a penalty from Pizzi and a late strike from Viktor Kovalenko handed the hosts victory.